Category definition

1. Building categories  based on:

     a. Mechanistic similarity
     b. Structural (empirical) similarity

2. Combining categories to assess toxicity of chemicals.

3. Using metabolism for category building






Supporting materials


Getting Started (pages 24-34)                                             pdf


Getting Started Quick Reference                                         pdf


Grouping chemicals                                                             pdf


Grouping Chemicals For Aquatic Toxicity                             pdf

(July 2013)                                                                              


Grouping Chemicals For Genotoxic Carcinogenicity            pdf

(July 2013)





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Defining categories