Selection of Representative Constituents for Unknown, Variable, Complex, or Biological Origin Substance Assessment Based on Hierarchical Clustering

Environmental Toxicology and Chemistry

September 2021

 

Darina G. Yordanova, Timothy J. Patterson, Colin M. North, Louise Camenzuli, Atanas S. Chapkanov, Todor S. Pavlov, Ovanes G. Mekenyan


The QSAR Toolbox automated read-across workflow for predicting acute oral toxicity: II. Verification and validation

Computational Toxicology

Volume 20, November 2021, 100194

 

Stela Kutsarova, Terry W. Schultz, Atanas Chapkanov, Daniela Cherkezova, Aycel Mehmed, Stoyanka Stoeva, Chanita Kuseva, Darina Yordanova, Marin Georgiev, Todor Petkov, Ovanes G. Mekenyan


Automated read-across workflow for predicting acute oral toxicity: I. The decision scheme in the QSAR toolbox

Regulatory Toxicology and Pharmacology

Volume 125, October 2021, 105015

 

Stela Kutsarova, Aycel Mehmed, Daniela Cherkezova, Stoyanka Stoeva, Marin Georgiev, Todor Petkov, Atanas Chapkanov, Terry   Schultz,  Ovanes Mekenyan


Criteria for quantitative assessment of metabolic similarity between chemicals. II. Application to human health endpoints

Computational Toxicology
Volume 19, August 2021, 100173

 

Chanita Kuseva,  Darina Yordanova,   Hristiana Ivanova, Gergana Poryazova, Irina Dermen, Antonia Kesova, Todor PAvlov, Terry   Schultz,    Ovanes Mekenyan


Assessing metabolic similarity for read-across predictions

Computational Toxicology
Volume 18, February 2021, 100160

 

Darina G.  Yordanova,  Terry W.  Schultz,  Chanita D.  Kuseva,  Ovanes G.  Mekenyan

 


Criteria for assessing the reliability of the predictions: II. CATALOGIC BOD and BCF base-line models

Computational Toxicology
Volume 17, February 2021, 100154

 

Iryna A.  Dermen Nadezhda H.  Dimitrova,  Terry W.  Schultz,  Ovanes G.  Mekenyan


Criteria for assessing the reliability of toxicity predictions: I. TIMES Ames mutagenicity model

Computational Toxicology
Volume 17, February 2021, 100143

 

Petko I.  Petkov Hristiana I.  Ivanova,  Terry W.  Schultz,  Ovanes G. Mekenyan

 


Computational material flow analysis for thousands of chemicals of emerging concern in European watersy model

Journal of Hazardous Materials
Volume 397, October 2020, 122655

 

Jos van Gils, Leo Posthuma, Ian T. Cousins, Werner Brack, Rolf Altenburger, Hans Baveco, Andreas Focks, Janek Greskowiak, Ralph Kühne, Stela Kutsarova, Claudia Lindim, Arjen Markus, Dik van de Meent, John Munthe, Rudy Schueder, Gerrit Schüürmann, Jaroslav Slobodnik, Dick de Zwart, Annemarie van Wezel


Modeling hazard assessment of chemicals based on adducts formation. I. A basis for inclusion of kinetic factors in simulating skin sensitization

Computational Toxicology
Volume 15, August 2020, 100130

 

Hristiana Ivanova, Gergana Dimitrova, Chanita Kuseva, Terry W. Schultz, Ovanes G. Mekenyan

 


UVCB substances II: Development of an endpoint‐nonspecific procedure for selection of computationally generated representative constituents

Environmental Toxicology and Chemistry

Volume 38, Issue 3, March 2019 pp 682-694

 

Stela S. Kutsarova,  Darina G. Yordanova, Yordan H. Karakolev, Stoyanka Stoeva, Mike Comber, Christopher B. Hughes, Eleni Vaiopoulou, Sabcho D. Dimitrov, Ovanes G. Mekenyan