Procedure for toxicological predictions based on mechanistic weight of evidences: Application to Ames mutagenicity

Computational Toxicology
Volume 12, November 2019, 100109

 

 

Petko I.  Petkov,  Chanita Kuseva, Stefan  Kotov,  Masamitsu  Honma,  Airi  Kitazawa,  Sunil  Kulkarni,  Terry W.  Schultz,  Ovanes G.Mekenyan

In silico mechanistically-based profiling module for acute oral toxicity

Computational Toxicology
Volume 12, November 2019, 100109

 

Daniela  Nedelcheva,  Stoyanka  Stoeva,  Sabcho  Dimitrov,  Ann  Detroyer,  Aziz  Fadli,  Reine  Note,  Delphine  Blanchet,  Ovanes  Mekenyan

The OECD QSAR Toolbox Starts Its Second Decade

Computational Toxicology, Methods in Molecular Biology,
Volume 1800, June 2018, pp 55-77

 

  • Terry W. Schultz,  Robert Diderich, Chanita D. Kuseva, Ovanes G. Mekenyan

Accounting for data variability, a key factor in in vivo/in vitro relationships: application to the skin sensitization potency (in vivo LLNA versus in vitro DPRA) example

Journal of Applied Toxicology

Volume 36 (12), December 2016, pp 1568-1578

 

S. Dimitrov, Ann Detroyer, C. Piroird, C. Gomes, J. Eilstein, T. Pauloin, C. Kuseva, H. Ivanova, I. Popova, Y. Karakolev, S. Ringeissen, O. Mekenyan

QSAR Toolbox – workflow and major functionalities

SAR and QSAR in Environmental Research

Volume 27(3), February 2016, pp 203-219

 

 

S. D. Dimitrov, R. Diderich, T. Sobanski, T. S. Pavlov, G. V. Chankov, A. S. Chapkanov, Y. H. Karakolev, S. G. Temelkov, R. A. Vasilev, K. D. Gerova, C. D. Kuseva, N. D. Todorova, A. M. Mehmed, M. Rasenberg & O. G. Mekenyan 

Towards AOP application – Implementation of an integrated approach to testing and assessment (IATA) into a pipeline tool for skin sensitization

Regulatory Toxicology and Pharmacology

Volume 69(3), August 2014, pp 529-545

 

Grace  Patlewicz,  Chanita  Kuseva,  Antonia  Kesova,  Ioanna  Popova,  Teodor  Zhechev,  Todor  Pavlov,  David W.  Roberts,  Ovanes Mekenyan

TIMES-SS – Recent refinements resulting from an industrial skin sensitisation consortium

SAR and QSAR in Environmental Research

Volume 25(5), May 2014, pp 367-391

 

G. Patlewicz, C. Kuseva, A. Mehmed, Y. Popova, G. Dimitrova, G. Ellis, R. Hunziker, P. Kern, L. Low, S. Ringeissen, D.W. Roberts & O. Mekenyan 

A Mechanistic Approach to Modeling Respiratory Sensitization

Chemical Research in Toxicology

Volume 27(2), January 2014, pp 219-239

 

  • Ovanes Mekenyan,  Grace Patlewicz, Chanita Kuseva, Ioanna Popova, Aycel Mehmed, Stefan Kotov, Teodor Zhechev, Todor Pavlov, Stanislav Temelkov, David W. Roberts

Simulation of chemical metabolism for fate and hazard assessment. V. Mammalian hazard assessment.

SAR and QSAR in Environmental Research

Volume 23, Issue 5-6, 553-606, 2012

 

O. Mekenyan,  S. Dimitrov,  T. Pavlov,  G. Dimitrova,  M. Todorov,  P. Petkov &  S. Kotov

 

Simulation of chemical metabolism for fate and hazard assessment. IV. Computer-based derivation of metabolic simulators from documented metabolism maps.

SAR and QSAR in Environmental Research  

Volume 23, Issue 5-6, 371-387, 2012

 

S. Karabunarliev,  S. Dimitrov,  T. Pavlov,  D. Nedelcheva &  O. Mekenyan