In silico predictions of sub-chronic effects: Read-across using metabolic relationships between parents and transformation products

Computational Toxicology 

Vol. 30, June 2024, 100314

 

Darina G. Yordanova, Chanita D. Kuseva, Hristiana Ivanova, Terry W. Schultz, Vanessa Rocha, Andreas Natsch, Heike Laue, Ovanes G. Mekenyan

 

Uncertainty in the results from oral repeated dose toxicity tests: Impact on regulatory classifications

Regulatory Toxicology and Pharmacology

Vol. 146, January 2024, 105541

 

Atanas Chapkanov, Terry W. Schultz, Ovanes Mekenyan

Estimating uncertainty in LLNA EC3 data and its impact on regulatory classifications

Regulatory Toxicology and Pharmacology

Vol. 139, March 2023, 105357

 

Atanas Chapkanov, Terry W. Schultz, Darina Yordanova, Kalin Kirilov, Hristiana Ivanova, Ovanes Mekenyan

Predicting explosive properties of chemicals accounting for thermodynamic and kinetic factors

Computational Toxicology 

Vol. 23, August 2022, 100230

 

Chanita Kuseva, Valentin Marinov, Todor Pavlov, Todor Petkov, Atanas Chapkanov, Detelina Dimitrova, Tobias Wombacher, Sarah Mullen-Hinkle, Wisdom Zhu, Michael Siebold, Ovanes Mekenyan

 

Assessment of uncertainty and credibility of predictions by the OECD QSAR Toolbox automated read-across workflow for predicting acute oral toxicity

Computational Toxicology

Volume 22, May 2022, 100219

 

Terry W. Schultz, Stela Kutsarova, Atanas Chapkanov, Ovanes G. Mekenyan

Estimating the reliability of simulated metabolism using documented data and theoretical knowledge. QSAR application

Computational Toxicology 

Vol. 22, May 2022, 100218

 

Irina A. Dermen, Hristiana I. Ivanova, Elena K. Kaloyanova, Nadezhda H. Dimitrova, Antonia D. Kesova, Todor S. Pavlov, Terry W. Schultz, Ovanes G. Mekenyan

 

Selection of Representative Constituents for Unknown, Variable, Complex, or Biological Origin Substance Assessment Based on Hierarchical Clustering

Environmental Toxicology and Chemistry

September 2021

 

Darina G. Yordanova, Timothy J. Patterson, Colin M. North, Louise Camenzuli, Atanas S. Chapkanov, Todor S. Pavlov, Ovanes G. Mekenyan

The QSAR Toolbox automated read-across workflow for predicting acute oral toxicity: II. Verification and validation

Computational Toxicology

Volume 20, November 2021, 100194

 

Stela Kutsarova, Terry W. Schultz, Atanas Chapkanov, Daniela Cherkezova, Aycel Mehmed, Stoyanka Stoeva, Chanita Kuseva, Darina Yordanova, Marin Georgiev, Todor Petkov, Ovanes G. Mekenyan

Automated read-across workflow for predicting acute oral toxicity: I. The decision scheme in the QSAR toolbox

Regulatory Toxicology and Pharmacology

Volume 125, October 2021, 105015

 

Stela Kutsarova, Aycel Mehmed, Daniela Cherkezova, Stoyanka Stoeva, Marin Georgiev, Todor Petkov, Atanas Chapkanov, Terry   Schultz,  Ovanes Mekenyan

Criteria for quantitative assessment of metabolic similarity between chemicals. II. Application to human health endpoints

Computational Toxicology
Volume 19, August 2021, 100173

 

Chanita Kuseva,  Darina Yordanova,   Hristiana Ivanova, Gergana Poryazova, Irina Dermen, Antonia Kesova, Todor PAvlov, Terry   Schultz,    Ovanes Mekenyan